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What is Sinex?

Sinex Tablet is used for Common cold, Cough, Runny nose, Cold, Congestion, Allergic and other conditions. Sinex Tablet may also be used for purposes not listed in this medication guide.
Sinex Tablet contains Caffeine, Chlorpheniramine Maleate, Paracetamol and Phenylpropanolamine as active ingredients.
Sinex Tablet works by increasing the pain threshold and increases the blood flow across the skin, heat loss and sweating; blocking H1-receptor sites on tissues; stimulating alpha-adrenergic receptors which produce vasoconstriction and reduces tissue edema and nasal congestion; antagonizing the adenosine receptors;
Biomedica International manufactures Sinex Tablet.
Detailed information related to Sinex Tablet's uses, composition, dosage, side effects and reviews is listed below.

Sinex Tablet Uses

Sinex Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
References: 1, 2, 3, 4, 5, 6, 7
Learn more: Uses

Sinex Tablet Working, Mechanism of Action and Pharmacology

Sinex Tablet improves the patient's condition by performing the following functions:
References: 8, 9, 10

Sinex Tablet - Composition and Active Ingredients

Sinex Tablet is composed of the following active ingredients (salts)
Please note that this medicine may be available in various strengths for each active ingredient listed above.

Sinex Tablet - Side-effects

The following is a list of possible side-effects that may occur from all constituting ingredients of Sinex Tablet. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
  • Irregular heart beat
  • Muscular weakness
  • Feeling of sickness
  • Skin reddening
  • Allergic reactions
  • Shortness of breath
  • Sinex Tablet may also cause side-effects not listed here.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
References: 8, 11, 12, 13, 14, 15
Learn more: Side-effects

Sinex Tablet - Precautions & How to Use

Before using Sinex Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
References: 16, 16, 18

Sinex Tablet - Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Sinex Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Sinex Tablet may interact with the following drugs and products:
  • Acebutolol
  • Alcohol
  • Antipsychotics
  • Atropine
  • Bromocriptine
  • Cimetidine
References: 16
Learn more: Interactions

Sinex Tablet - Contraindications

Hypersensitivity to Sinex Tablet is a contraindication. In addition, Sinex Tablet should not be used if you have the following conditions:
  • Glaucoma
  • Hepatic impairment
  • Hypersensitivity
  • Hypertension
  • Hyperthyroidism
  • Intestinal obstruction
Learn more: Contraindications

Where to Buy Sinex Tablet

Click here to find nearby pharmacies/medical stores where you can buy Sinex Tablet.

Sinex Tablet - Frequently asked Questions

  • Is Sinex Tablet safe to consume or apply when pregnant?
    • Paracetamol: Please consult with your doctor for case-specific recommendations.
    • Chlorpheniramine Maleate: Please consult with your doctor for case-specific recommendations.
    • Phenylpropanolamine: Please consult with your doctor for case-specific recommendations.
    • Caffeine: Please consult with your doctor for case-specific recommendations.
    References: 16 18
  • Is Sinex Tablet safe while breastfeeding?
    • Paracetamol: Please discuss the risks and benefits with your doctor.
    • Chlorpheniramine Maleate: Please discuss the risks and benefits with your doctor.
    • Phenylpropanolamine: No
    • Caffeine: Please discuss the risks and benefits with your doctor.
    References: 16 18
  • Can Sinex Tablet be used for common cold and cough?
    Yes, common cold and cough are among the most common reported uses for Sinex Tablet. Please do not use Sinex Tablet for common cold and cough without consulting first with your doctor. Click here to find out what other patients report as common uses for Sinex Tablet.
  • How long do I need to use Sinex Tablet before I see improvement of my conditions? website users have reported same day and 2 weeks as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Sinex Tablet. Click here to find out what other patients report as time for effectiveness for Sinex Tablet.
  • At what frequency do I need to use Sinex Tablet? website users have reported twice a day and once a day as the most common frequency of using Sinex Tablet. Please follow your doctor's advice on how often you need to Sinex Tablet. Click here to find out what other patients report as frequency of using Sinex Tablet.
  • Should I consume Sinex Tablet empty stomach, before food or after food? website users have most commonly reported consuming Sinex Tablet after food. However, this may not be reflective of how you should consume this medicine. Please follow your doctor's advice on how you should use this medicine. Click here to find out what other patients report as timing of using Sinex Tablet.
  • Is it safe to drive or operate heavy machinery when consuming?
    If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Sinex Tablet medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Sinex Tablet. Always consult with your doctor for recommendations specific to your body and health conditions.
  • Is this medicine or product addictive or habit forming?
    Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
  • Can it be stopped immediately or do I have to slowly ween off consumption?
    Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on Sinex Tablet

Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
References: 19, 20, 21, 22

Overdosage of Sinex Tablet

  • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Sinex Tablet, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
  • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
  • Please consult your physician or pharmacist or product package for more information.
References: 23, 24, 25

Storage of Sinex Tablet

  • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
  • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Sinex Tablet.
References: 26, 27, 28, 29

Expired Sinex Tablet

  • Taking a single dose of expired Sinex Tablet is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
References: 30, 31

Dosage Information

Please consult your physician or pharmacist or refer to product package.

Questions - Sinex Tablet

News and Updates

Latest news and updates related to Sinex Tablet. Subscribe to get latest posts via email or subscribe to a RSS feed.
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Sinex Tablet - Packages and Strengths

Sinex Tablet is available in the following packages and strengths
Sinex Tablet - Packages: 10 Tablet

Sinex Tablet - Manufacturers

The medicine is manufactured by the following companies

Sinex Tablet - Demographic Information


  1. DailyMed LABEL: ACETAMINOPHEN - acetaminophen tablet, coated - Accessed: October 12, 2016.
  2. Postgrad Med J. 1982 Jul; 58(681): 422–423. PMCID: PMC2426514 Controlled trial of terfenadine and chlorpheniramine maleate in perennial rhinitis - Accessed: October 12, 2016.
  3. Source: MeSH Record Name: Phenylpropanolamine - Accessed: October 12, 2016.
  4. Dailymed Caffeine tablet - Accessed: October 12, 2016.
  5. Kugelman A, Durand M (2011). "A comprehensive approach to the prevention of bronchopulmonary dysplasia". Pediatr Pulmonol. 46 (12): 1153–65. doi:10.1002/ppul.21508. PMID 21815280. - Accessed: October 12, 2016.
  6. Schmidt B (2005). "Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5 years in the international Caffeine for Apnea of Prematurity (CAP) trial". Biol. Neonate. 88 (3): 208–13. doi:10.14. PMID 16210843. - Accessed: October 12, 2016.
  7. Mathew OP (2011). "Apnea of prematurity: pathogenesis and management strategies". J Perinatol. 31 (5): 302–10. doi:10.1038/jp.2010.126. PMID 21127467. - Accessed: October 12, 2016. (Accessed 10/13/16)
  8. Pubchem Acetaminophen - Accessed: October 12, 2016.
  9. Carlsson, A.; Linqvist M. (1969). "Central and peripheral monoaminergic membrane-pump blockade by some addictive analgesics and antihistamines". Journal of Pharmacy and Pharmacology. 21 (7): 460–464. doi:10.1111/j.2042-7158.1969.tb08287.x. PMID 4390069. - Accessed: October 12, 2016.
  10. McEvoy, G.K. (ed.). American Hospital Formulary Service-Drug Information 19 98. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 1998 (Plus Supplements)., p. 1062 from HSDB Record Name: PHENYLPROPANOLAMINE - Accessed: October 12, 2016. dbs+hsdb:+++14838-15-4
  11. Hasenöhrl, R. U.; Weth, K.; Huston, J. P. (1999). "Intraventricular infusion of the histamine H1 receptor antagonist chlorpheniramine improves maze performance and has anxiolytic-like effects in aged hybrid Fischer 344×Brown Norway rats". Experimental Brain Research. 128 (4): 435–440. doi:10.1007/s. PMID 10541737. - Accessed: October 12, 2016.
  12. Lake CR et al; Am J Med 89 (2): 195-208 (1990) from HSDB Record Name: PHENYLPROPANOLAMINE - Accessed: October 12, 2016.
  13. Daniels JW, Molé PA, Shaffrath JD, Stebbins CL (1998). "Effects of caffeine on blood pressure, heart rate, and forearm blood flow during dynamic leg exercise". Journal of applied physiology. 85 (1): 154–9. PMID 9655769. - Accessed: October 12, 2016.
  14. D. Bracco, Ferrarra JM, Arnaud MJ, Jéquier E, Schutz Y (1995). "Effects of caffeine on energy metabolism, heart rate, and methylxanthine metabolism in lean and obese women". American Journal of Physiology. 269 (4): E671–8. PMID 7485480. - Accessed: October 12, 2016.
  15. Mahmud A, Feely J (2001). "Acute effect of caffeine on arterial stiffness and aortic pressure waveform". Hypertension. 38 (2): 227–31. doi:10.1161/01.HYP.38.2.227. PMID 11509481. - Accessed: October 12, 2016. (Accessed 10/13/16)
  16. Dailymed label: CHLORPHENIRAMINE MALEATE- chlorpheniramine maleate tablet. - Accessed: October 12, 2016.
  17. Dailymed label: CHLORPHENIRAMINE MALEATE- chlorpheniramine maleate tablet. - Accessed: October 12, 2016.
  18. Dailymed Caffeine - Accessed: October 12, 2016. (Accessed 10/13/16)
  19. - Accessed: July 14, 2016.
  20. - Accessed: July 3, 2016.
  21. Cancer.Net (2014). - Accessed: July 3, 2016.
  22. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). - Accessed: May 28, 2016.
  23. National Institute of Drug Abuse (2010). - Accessed: July 21, 2016.
  24. eMedicinehealth (2016). - Accessed: July 21, 2016.
  25. Centers for Disease Control and Prevention (2010). - Accessed: July 21, 2016.
  26. Centers for Disease Control and Prevention. December 12, 2011. - Accessed: June 10, 2016.
  27. The Center for Improving Medication Management and the National Council on Patient Information and Education. - Accessed: June 10, 2016.
  28. U.S. Food and Drug Administration. December 24, 2013. - Accessed: June 10, 2016.
  29. World Health Organization: - Accessed: July 1, 2016.
  30. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
  31. Harvard Medical School (2016). - Accessed: May 1, 2016.

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APA Style Citation

  • Sinex Tablet - Uses, Side-effects, Reviews, and Precautions - Biomedica International - - India. (n.d.). Retrieved January 17, 2018, from

MLA Style Citation

  • "Sinex Tablet - Uses, Side-effects, Reviews, and Precautions - Biomedica International - - India" N.p., n.d. Web. 17 Jan. 2018.

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  • "Sinex Tablet - Uses, Side-effects, Reviews, and Precautions - Biomedica International - - India" Accessed January 17, 2018.

Last updated date

This page was last updated on 1/16/2018.
This page provides information for Sinex Tablet in English.
Read Reviews » Sinex Tablet

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