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What is Neurobion?

Neurobion Injection is used for Treatment of vitamin b12 deficiency associated with addisonian anemia, Gluten enteropathy or sprue, Small bowel bacterial overgrowth, Total or partial gastrectomy, Fish tapeworm infestation, Malignancy of pancreas or bowel, Or folic acid deficiency, Clogged arteries, Mental disorders, High cholesterol, Fatigue, Mental disorder and other conditions. Neurobion Injection may also be used for purposes not listed in this medication guide.
Neurobion Injection contains Cobalamine, Pyridoxine and Thiamine as active ingredients.
Neurobion Injection works by relaxing the nerve signals to the brain; modifying the electrical activity thus relaxing and slowing overactive heart muscles; contributing to growth, cell reproduction, hematopoiesis, nucleoprotein and myelin synthesis;
Merck manufactures Neurobion Injection.
Detailed information related to Neurobion Injection's uses, composition, dosage, side effects and reviews is listed below.

Neurobion Injection Uses

Neurobion Injection Working, Mechanism of Action and Pharmacology

Neurobion Injection improves the patient's condition by performing the following functions:
  • Relaxing the nerve signals to the brain.
  • Modifying the electrical activity thus relaxing and slowing overactive heart muscles.
  • Contributing to growth, cell reproduction, hematopoiesis, nucleoprotein and myelin synthesis.
References: 2, 3

Neurobion Injection - Composition and Active Ingredients

Neurobion Injection is composed of the following active ingredients (salts)
Please note that this medicine may be available in various strengths for each active ingredient listed above.

Neurobion Injection - Side-effects

The following is a list of possible side-effects that may occur from all constituting ingredients of Neurobion Injection. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
References: 1, 2
Report:
Learn more: Side-effects

Neurobion Injection - Precautions & How to Use

Before using Neurobion Injection, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
  • Anaphylactic shock
  • Avoid taking folic acid in place of this product
  • Breastfeeding
  • Difficulty in breathing
  • Early Leber’s disease
  • Hives
References: 1, 1, 2, 2

Neurobion Injection - Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Neurobion Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Neurobion Injection may interact with the following drugs and products:
  • Antibiotics
  • Colchicine
  • Digoxin
  • Furosemide
  • Heavy alcohol intake
  • Isoniazid
References: 1, 2
Learn more: Interactions

Neurobion Injection - Contraindications

Hypersensitivity to Neurobion Injection is a contraindication. In addition, Neurobion Injection should not be used if you have the following conditions:
References: 1, 2
Learn more: Contraindications

Where to Buy Neurobion Injection

Click here to find nearby pharmacies/medical stores where you can buy Neurobion Injection.

Neurobion Injection - Frequently asked Questions

  • Is Neurobion Injection safe to consume or apply when pregnant?
    • Thiamine: Yes
    • Pyridoxine: Please consult with your doctor for case-specific recommendations.
    • Cobalamine: Yes
    References: 1 2
  • Is Neurobion Injection safe while breastfeeding?
    • Thiamine: Yes
    • Pyridoxine: Please discuss the risks and benefits with your doctor.
    • Cobalamine: Yes
    References: 1 2
  • Can Neurobion Injection be used for treatment of vitamin b12 deficiency associated with addisonian anemia, gluten enteropathy or sprue, small bowel bacterial overgrowth, total or partial gastrectomy, fish tapeworm infestation, malignancy of pancreas or bowel, or folic acid deficiency and clogged arteries?
    Yes, treatment of vitamin b12 deficiency associated with addisonian anemia, gluten enteropathy or sprue, small bowel bacterial overgrowth, total or partial gastrectomy, fish tapeworm infestation, malignancy of pancreas or bowel, or folic acid deficiency and clogged arteries are among the most common reported uses for Neurobion Injection. Please do not use Neurobion Injection for treatment of vitamin b12 deficiency associated with addisonian anemia, gluten enteropathy or sprue, small bowel bacterial overgrowth, total or partial gastrectomy, fish tapeworm infestation, malignancy of pancreas or bowel, or folic acid deficiency and clogged arteries without consulting first with your doctor. Click here and view survey results to find out what other patients report as common uses for Neurobion Injection.
  • How long do I need to use Neurobion Injection before I see improvement of my conditions?
    all4insure.ru website users have reported 1 month and 2 weeks as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Neurobion Injection. Click here and view survey results to find out what other patients report as time for effectiveness for Neurobion Injection.
  • At what frequency do I need to use Neurobion Injection?
    all4insure.ru website users have reported once a day and twice a day as the most common frequency of using Neurobion Injection. Please follow your doctor's advice on how often you need to Neurobion Injection. Click here and view survey results to find out what other patients report as frequency of using Neurobion Injection.
  • Should I consume Neurobion Injection empty stomach, before food or after food?
    all4insure.ru website users have most commonly reported consuming Neurobion Injection after food. However, this may not be reflective of how you should consume this medicine. Please follow your doctor's advice on how you should use this medicine. Click here and view survey results to find out what other patients report as timing of using Neurobion Injection.
  • Is it safe to drive or operate heavy machinery when consuming?
    If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Neurobion Injection medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Neurobion Injection. Always consult with your doctor for recommendations specific to your body and health conditions.
  • Is this medicine or product addictive or habit forming?
    Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
  • Can it be stopped immediately or do I have to slowly ween off consumption?
    Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on Neurobion Injection

Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
References: 4, 5, 6, 7

Overdosage of Neurobion Injection

  • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Neurobion Injection, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
  • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
  • Please consult your physician or pharmacist or product package for more information.
References: 8, 9, 10

Storage of Neurobion Injection

  • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
  • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Neurobion Injection.
References: 11, 12, 13, 14

Expired Neurobion Injection

  • Taking a single dose of expired Neurobion Injection is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
References: 15, 16

Dosage Information

Please consult your physician or pharmacist or refer to product package.

Questions - Neurobion Injection

Yes, Neurobion is safe during pregnancy, but it is always suggested to be taken on doctor's recommendation. The active ingredients of Neurobion are Vitamin B1, Vitamin B12 and Vitamin B6. It is used to treat neurological disturbances, mental problems, vitamin B12 deficiency, heart problem, pregnancy complications, and anaemia etc. US Food and Drug Administration (FDA) has specified vitamin B1 (thiamine), B6 (pyridoxine) as a pregnancy category A drug which means studies have failed to demonstrate a risk to the fetus in all trimester of pregnancy.

Vitamin B types such as B1 (thiamine), B12 (cyanocobalamin) and B6 (pyridoxine hydrochloride) are the water-soluble vitamins that are naturally present in some foods or available as the dietary supplements and prescription medication. They play important roles in cell metabolism.

A study published in 2015 in the journal of Cochrane Database of Systematic Reviews showed that vitamin B6 protects against certain congenital malformations, pre‐eclampsia and preterm birth. NIH study found that untreated and undetected vitamin B12 deficiency in infants can increase the risk of neurological damage.

Women before taking Neurobion are advised to notify their gynaecologist if they become pregnant or intend to become pregnant.

References
1. NIH Vitamin B12 URL: Accessed January 09, 2018
2. Wikipedia Thiamine URL: Accessed January 09, 2018
3. Salam RA, Zuberi NF, Bhutta ZA. Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes. Cochrane Database Syst Rev. 2015;(6):CD000179 URL: Accessed January 09, 2018
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Yes, Neurobion is safe during pregnancy, but it is always suggested to be taken on doctor's recommendation. The active ingredients of Neurobion are Vitamin B1, Vitamin B12 and Vitamin B6. It is used to treat neurological disturbances, mental problems, vitamin B12 deficiency, heart problem, pregnancy complications, and anaemia etc. US Food and Drug Administration (FDA) has specified vitamin B1 (thiamine), B6 (pyridoxine) as a pregnancy category A drug which means studies have failed to demonstrate a risk to the fetus in all trimester of pregnancy.

Vitamin B types such as B1 (thiamine), B12 (cyanocobalamin) and B6 (pyridoxine hydrochloride) are the water-soluble vitamins that are naturally present in some foods or available as the dietary supplements and prescription medication. They play important roles in cell metabolism.

A study published in 2015 in the journal of Cochrane Database of Systematic Reviews showed that vitamin B6 protects against certain congenital malformations, pre‐eclampsia and preterm birth. NIH study found that untreated and undetected vitamin B12 deficiency in infants can increase the risk of neurological damage.

Women before taking Neurobion are advised to notify their gynaecologist if they become pregnant or intend to become pregnant.

References
1. NIH Vitamin B12 URL: Accessed January 09, 2018
2. Wikipedia Thiamine URL: Accessed January 09, 2018
3. Salam RA, Zuberi NF, Bhutta ZA. Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes. Cochrane Database Syst Rev. 2015;(6):CD000179 URL: Accessed January 09, 2018
Share
Share the link to this answer

News and Updates

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Neurobion Injection - Packages and Strengths

Neurobion Injection is available in the following packages and strengths
Neurobion Injection - Packages: 3ML Injection
Neurobion Injection - Strengths: 100MG+100MG+1MG

Neurobion Injection - Manufacturers

The medicine is manufactured by the following companies

Neurobion Injection - Demographic Information

References

  1. DailyMed LABEL: PYRIDOXINE HYDROCHLORIDE - pyridoxine hydrochloride injection, solution - Accessed: October 12, 2016. (Accessed on 2/6/17)
  2. Dailymed Cyanocobalamin - Accessed: October 12, 2016. Accessed on 11/14/2016
  3. Pubchem Pyridoxine - Accessed: October 12, 2016. (Accessed on 2/6/17)
  4. - Accessed: July 14, 2016.
  5. - Accessed: July 3, 2016.
  6. Cancer.Net (2014). - Accessed: July 3, 2016.
  7. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). - Accessed: May 28, 2016.
  8. National Institute of Drug Abuse (2010). - Accessed: July 21, 2016.
  9. eMedicinehealth (2016). - Accessed: July 21, 2016.
  10. Centers for Disease Control and Prevention (2010). - Accessed: July 21, 2016.
  11. Centers for Disease Control and Prevention. December 12, 2011. - Accessed: June 10, 2016.
  12. The Center for Improving Medication Management and the National Council on Patient Information and Education. - Accessed: June 10, 2016.
  13. U.S. Food and Drug Administration. December 24, 2013. - Accessed: June 10, 2016.
  14. World Health Organization: - Accessed: July 1, 2016.
  15. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
  16. Harvard Medical School (2016). - Accessed: May 1, 2016.

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  • Neurobion Injection - Uses, Side-effects, Reviews, and Precautions - Merck - all4insure.ru - India. (n.d.). Retrieved January 21, 2018, from http://all4insure.ru/neurobion-injection

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  • "Neurobion Injection - Uses, Side-effects, Reviews, and Precautions - Merck - all4insure.ru - India" all4insure.ru. Accessed January 21, 2018. http://all4insure.ru/neurobion-injection.

Alternate forms of Neurobion Injection

Last updated date

This page was last updated on 1/16/2018.
This page provides information for Neurobion Injection in English.
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