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What is Neurobion Forte?

Neurobion Forte Tablet is used for Arthritis, Vitamin b 12 deficiencies, Diabetic neuropathy, Arthritic, High cholesterol, Clogged arteries and other conditions. Neurobion Forte Tablet may also be used for purposes not listed in this medication guide.
Neurobion Forte Tablet contains Calcium Pantothenate, Cyanocobalamin, Nicotinamide, Pyridoxine and Thiamine as active ingredients.
Neurobion Forte Tablet works by protecting cells against peroxidative damage by increasing the level of glutathione; helping tissue in respiration and metabolism of fats, protein thus lowers blood cholesterol by inhibiting the synthesis of LDL; normalizing the formation of red blood cells and nerve tissues; modifying the electrical activity thus relaxing and slowing overactive heart muscles; relaxing the nerve signals to the brain;
Merck manufactures Neurobion Forte Tablet.
Detailed information related to Neurobion Forte Tablet's uses, composition, dosage, side effects and reviews is listed below.

Neurobion Forte Tablet Uses

Neurobion Forte Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
References: 1, 2, 3, 4, 5
Report:
Learn more: Uses

Neurobion Forte Tablet Working, Mechanism of Action and Pharmacology

Neurobion Forte Tablet improves the patient's condition by performing the following functions:
References: 4, 6, 7, 8

Neurobion Forte Tablet - Composition and Active Ingredients

Neurobion Forte Tablet is composed of the following active ingredients (salts)
Please note that this medicine may be available in various strengths for each active ingredient listed above.

Neurobion Forte Tablet - Side-effects

The following is a list of possible side-effects that may occur from all constituting ingredients of Neurobion Forte Tablet. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
References: 4, 5, 9, 10
Report:
Learn more: Side-effects

Neurobion Forte Tablet - Precautions & How to Use

Before using Neurobion Forte Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
  • Breastfeeding
  • Difficulty in breathing
  • Do not consume if allergic to any ingredient in the medicine
  • Do not consume if pregnant or breastfeeding
  • Do not use the medicine if suffering from renal or hepatic impairment
  • Hives
References: 4, 4, 5, 5

Neurobion Forte Tablet - Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Neurobion Forte Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Neurobion Forte Tablet may interact with the following drugs and products:
  • Abacavir
  • Alcohol
  • Carbamazepine
  • Chloramphenicol
  • Cholestyramine
  • Ciprofloxacin
References: 4, 5
Learn more: Interactions

Neurobion Forte Tablet - Contraindications

Hypersensitivity to Neurobion Forte Tablet is a contraindication. In addition, Neurobion Forte Tablet should not be used if you have the following conditions:
  • Active peptic ulcer
  • Acute myocardial infarction
  • Atrophic gastritis
  • Cardiac arrhythmias
  • Condition of increased mast cells
  • Diabetes mellitus
References: 4, 5
Learn more: Contraindications

Where to Buy Neurobion Forte Tablet

Click here to find nearby pharmacies/medical stores where you can buy Neurobion Forte Tablet.

Neurobion Forte Tablet - Frequently asked Questions

  • Is Neurobion Forte Tablet safe to consume or apply when pregnant?
    • Calcium Pantothenate: Please consult with your doctor for case-specific recommendations.
    • Nicotinamide: Please consult with your doctor for case-specific recommendations.
    • Cyanocobalamin: Please consult with your doctor for case-specific recommendations.
    • Pyridoxine: Please consult with your doctor for case-specific recommendations.
    • Thiamine: Yes
    References: 4 5
  • Is Neurobion Forte Tablet safe while breastfeeding?
    • Calcium Pantothenate: Please discuss the risks and benefits with your doctor.
    • Nicotinamide: Please discuss the risks and benefits with your doctor.
    • Cyanocobalamin: Please discuss the risks and benefits with your doctor.
    • Pyridoxine: Please discuss the risks and benefits with your doctor.
    • Thiamine: Yes
    References: 4 5
  • Can Neurobion Forte Tablet be used for arthritis and vitamin b 12 deficiencies?
    Yes, arthritis and vitamin b 12 deficiencies are among the most common reported uses for Neurobion Forte Tablet. Please do not use Neurobion Forte Tablet for arthritis and vitamin b 12 deficiencies without consulting first with your doctor. Click here to find out what other patients report as common uses for Neurobion Forte Tablet.
  • How long do I need to use Neurobion Forte Tablet before I see improvement of my conditions?
    all4insure.ru website users have reported same day and 1 week as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Neurobion Forte Tablet. Click here to find out what other patients report as time for effectiveness for Neurobion Forte Tablet.
  • At what frequency do I need to use Neurobion Forte Tablet?
    all4insure.ru website users have reported once a day and twice a day as the most common frequency of using Neurobion Forte Tablet. Please follow your doctor's advice on how often you need to Neurobion Forte Tablet. Click here to find out what other patients report as frequency of using Neurobion Forte Tablet.
  • Should I consume Neurobion Forte Tablet empty stomach, before food or after food?
    all4insure.ru website users have most commonly reported consuming Neurobion Forte Tablet after food. However, this may not be reflective of how you should consume this medicine. Please follow your doctor's advice on how you should use this medicine. Click here to find out what other patients report as timing of using Neurobion Forte Tablet.
  • Is it safe to drive or operate heavy machinery when consuming?
    If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Neurobion Forte Tablet medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Neurobion Forte Tablet. Always consult with your doctor for recommendations specific to your body and health conditions.
  • Is this medicine or product addictive or habit forming?
    Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
  • Can it be stopped immediately or do I have to slowly ween off consumption?
    Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on Neurobion Forte Tablet

Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
References: 11, 12, 13, 14

Overdosage of Neurobion Forte Tablet

  • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Neurobion Forte Tablet, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
  • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
  • Please consult your physician or pharmacist or product package for more information.
References: 15, 16, 17

Storage of Neurobion Forte Tablet

  • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
  • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Neurobion Forte Tablet.
References: 18, 19, 20, 21

Expired Neurobion Forte Tablet

  • Taking a single dose of expired Neurobion Forte Tablet is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
References: 22, 23

Dosage Information

Please consult your physician or pharmacist or refer to product package.

Questions - Neurobion Forte Tablet

The safety profile of Neurobion Forte is unknown. The active ingredients of Neurobion Forte are calcium pantothenate, cyanocobalamin, nicotinamide, pyridoxine and thiamine. It is used to treat diabetic neuropathy, high cholesterol, clogged arteries, vitamin B3 deficiency, arthritis, anaemia and diarrhoea, folic acid deficiency, etc. US Food and Drug Administration (FDA) has specified Nicotinamide as a pregnancy category C drug which indicates that animal studies show an adverse effect on the fetus, but there are no teratogenic studies of nicotinamide in pregnant women and vitamin B1 (thiamine), B6 (pyridoxine) belongs to pregnancy category A, which means studies have failed to demonstrate a risk to the fetus in all trimester of pregnancy.

A study published in 2015 in the journal of Cochrane Database of Systematic Reviews showed that vitamin B6 protects against certain congenital malformations, pre‐eclampsia and preterm birth. Studies suggest that normal amount of Nicotinamide is safe during pregnancy, but high doses may cause liver problems. Another study found that untreated and undetected vitamin B12 deficiency in infants can increase the risk of neurological damage.

Women before taking Neurobion Fort are advised to notify their gynaecologist if they become pregnant or intend to become pregnant.

References
1. Wikipedia Nicotinamide URL: Accessed January 09, 2018
2. NIH Vitamin B12 URL: Accessed January 09, 2018
3. Wikipedia Thiamine URL: Accessed January 09, 2018
4. Salam RA, Zuberi NF, Bhutta ZA. Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes. Cochrane Database Syst Rev. 2015;(6):CD000179 URL: Accessed January 09, 2018
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News and Updates

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Neurobion Forte Tablet - Packages and Strengths

Neurobion Forte Tablet is available in the following packages and strengths
Neurobion Forte Tablet - Packages: 10 Tablet, 50 Tablet

Neurobion Forte Tablet - Manufacturers

The medicine is manufactured by the following companies

Neurobion Forte Tablet - Demographic Information

References

  1. Source: HSDB Record Name: D-Pantothenic Acid - Accessed: October 12, 2016.
  2. McEvoy, G.K. (ed.). American Hospital Formulary Service. AHFS Drug Information. American Society of Health-System Pharmacists, Bethesda, MD. 2007., p. 3622 Source: HSDB Record Name: NICOTINAMIDE - Accessed: October 12, 2016.
  3. Source: MeSH Record Name: Niacinamide - Accessed: October 12, 2016.
  4. Dailymed Cyanocobalamin - Accessed: October 12, 2016. (Accessed on 11/5/16)
  5. DailyMed LABEL: PYRIDOXINE HYDROCHLORIDE - pyridoxine hydrochloride injection, solution - Accessed: October 12, 2016. (Accessed on 2/6/17)
  6. Source: MeSH Record Name: Pantothenic Acid - Accessed: October 12, 2016.
  7. Young, L.Y., M.A. Koda-Kimble (eds.). Applied Therapeutics. The Clinical Use of Drugs. 6th ed. Vancouver, WA., Applied Therapeutics, Inc. 1995., p. 48-7 from HSDB Record Name: NICOTINAMIDE - Accessed: October 12, 2016.
  8. Pubchem Pyridoxine - Accessed: October 12, 2016. (Accessed on 2/6/17)
  9. Debourdeau PM et al; Ann Pharmacother 35 (4): 424-6 (2001). Available from, as of March 16, 2010: from HSDB Record Name: D-Pantothenic Acid - Accessed: October 12, 2016.
  10. Cosmetic Ingredient Review (CIR) Expert Panel; Final Report of the Safety Assessment of Niacinamide and Niacin; Intl J of Toxicology 24 (Suppl 5): 1-31 (2005) p.6 Source: HSDB Record Name: NICOTINAMIDE - Accessed: October 12, 2016.
  11. - Accessed: July 14, 2016.
  12. - Accessed: July 3, 2016.
  13. Cancer.Net (2014). - Accessed: July 3, 2016.
  14. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). - Accessed: May 28, 2016.
  15. National Institute of Drug Abuse (2010). - Accessed: July 21, 2016.
  16. eMedicinehealth (2016). - Accessed: July 21, 2016.
  17. Centers for Disease Control and Prevention (2010). - Accessed: July 21, 2016.
  18. Centers for Disease Control and Prevention. December 12, 2011. - Accessed: June 10, 2016.
  19. The Center for Improving Medication Management and the National Council on Patient Information and Education. - Accessed: June 10, 2016.
  20. U.S. Food and Drug Administration. December 24, 2013. - Accessed: June 10, 2016.
  21. World Health Organization: - Accessed: July 1, 2016.
  22. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
  23. Harvard Medical School (2016). - Accessed: May 1, 2016.

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Last updated date

This page was last updated on 1/16/2018.
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