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What is Dydrogesterone?

Dydrogesterone is used for Hormone replacement therapy, Infertility due to luteal insufficiency, Infertility, Dysfunctional uterine bleeding and irregular cycles, Miscarriage, Recurrent miscarriage due to progesterone deficiency and other conditions. This salt may also be used for purposes not listed in this medication guide. Detailed information related to Dydrogesterone's uses, side-effects, reviews, questions, interactions, and precautions is as follows:

Dydrogesterone Uses

Dydrogesterone is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
References: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
Learn more: Uses

Dydrogesterone Working, Mechanism of Action and Pharmacology

Dydrogesterone improves the patient's condition by performing the following functions:
References: 11

Dydrogesterone - Side-effects

The following is a list of possible side-effects that may occur in medicines that contain Dydrogesterone. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
References: 12, 13
Learn more: Side-effects

Dydrogesterone - Precautions & How to Use

Before using Dydrogesterone, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
  • Abnormal bleeding
  • Breast cancer
  • Cancer of the uterus lining
  • Depression
  • Do not take in combination with estrogen
  • Porphyria

Where to Buy Dydrogesterone

Click here to find nearby pharmacies/medical stores where you can buy Dydrogesterone.

Dydrogesterone - Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Dydrogesterone may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Dydrogesterone may interact with the following drugs and products:
Learn more: Interactions

Dydrogesterone - Contraindications

Hypersensitivity to Dydrogesterone is a contraindication. In addition, Dydrogesterone should not be used if you have the following conditions:
  • Advanced pregnancy
  • Blood clots disorder
  • Brain cancer
  • Breast cancer
  • Breastfeeding mothers
  • Children under age 18 years
Learn more: Contraindications

Dydrogesterone - Frequently asked Questions

  • Is Dydrogesterone safe to consume or apply when pregnant?
  • Is Dydrogesterone safe while breastfeeding?
  • Can Dydrogesterone be used for hormone replacement therapy and infertility due to luteal insufficiency?
    Yes, hormone replacement therapy and infertility due to luteal insufficiency are among the most common reported uses for Dydrogesterone. Please do not use Dydrogesterone for hormone replacement therapy and infertility due to luteal insufficiency without consulting first with your doctor. Click here to find out what other patients report as common uses for Dydrogesterone.
  • How long do I need to use Dydrogesterone before I see improvement of my conditions? website users have reported within 2 hours and 1 day as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Dydrogesterone. Click here to find out what other patients report as time for effectiveness for Dydrogesterone.
  • At what frequency do I need to use Dydrogesterone? website users have reported once a day and twice a day as the most common frequency of using Dydrogesterone. Please follow your doctor's advice on how often you need to Dydrogesterone. Click here to find out what other patients report as frequency of using Dydrogesterone.
  • Should I consume Dydrogesterone empty stomach, before food or after food? website users have most commonly reported consuming Dydrogesterone after food. However, this may not be reflective of how you should consume this medicine. Please follow your doctor's advice on how you should use this medicine. Click here to find out what other patients report as timing of using Dydrogesterone.
  • Is it safe to drive or operate heavy machinery when consuming?
    If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Dydrogesterone medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Dydrogesterone. Always consult with your doctor for recommendations specific to your body and health conditions.
  • Is this medicine or product addictive or habit forming?
    Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
  • Can it be stopped immediately or do I have to slowly ween off consumption?
    Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on Dydrogesterone

Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
References: 14, 15, 16, 17

Overdosage of Dydrogesterone

  • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Dydrogesterone, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
  • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
  • Please consult your physician or pharmacist or product package for more information.
References: 18, 19, 20

Storage of Dydrogesterone

  • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
  • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Dydrogesterone.
References: 21, 22, 23, 24

Expired Dydrogesterone

  • Taking a single dose of expired Dydrogesterone is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
References: 25, 26

Dosage Information

Please consult your physician or pharmacist or refer to product package.

News and Updates

Latest news and updates related to Dydrogesterone. Subscribe to get latest posts via email or subscribe to a RSS feed.
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Dydrogesterone - Demographic Information


  1. Trivedi P; Selvaraj K; Mahapatra PD; Srivastava S; Malik S. (2007). "Effective post-laparoscopic treatment of endometriosis with dydrogesterone.". Gynecol Endocrinol. 23 (Suppl 1): 73–6. doi:10.1701669583. PMID 17943543. - Accessed: October 12, 2016.
  2. Panay N; Pritsch M; Alt J. (2007). "Cyclical dydrogesterone in secondary amenorrhea: results of a double-blind, placebo-controlled, randomized study.". Gynecol Endocrinol. 23: 611–8. doi:10.1701582554. PMID 17891596. - Accessed: October 12, 2016.
  3. "A Comparative Study between Norethisterone Progestogens and Dydrogesterone in the Treatment of Dysfunctional Uterine Bleeding" (PDF). Science Publications. - Accessed: October 12, 2016.
  4. Tomic V, Tomic J, Klaic DZ, Kasum M, Kuna K (2014). "Oral dydrogesterone versus vaginal progesterone gel in the luteal phase support: randomized controlled trial.". Eur J Obstet Gynecol Reprod Biol. 186 (1): 49–53. doi:10.1016/j.ejogrb.2014.11.002. PMID 25622239. - Accessed: October 12, 2016.
  5. Linden M; Buckingham K; Farquhar C; Kremer JA; Metwally M. (2011). "Luteal phase support for assisted reproduction cycles.". Cochrane Database Syst Rev. 10 (CD009154). doi:10.1.CD009154.pub2. PMID 21975790 - Accessed: October 12, 2016.
  6. Carp H (2015). "A systematic review of dydrogesterone for the treatment of recurrent miscarriage.". Gynecol Endocrinol. 31: 1–9. doi:10.3.2015.1006618. PMID 25765519. - Accessed: October 12, 2016.
  7. Carp H (2012). "A systematic review of dydrogesterone for the treatment of threatened miscarriage.". Gynecol Endocrinol. 12 (983): 90. doi:10.3.2012.702875. PMID 22794306. - Accessed: October 12, 2016.
  8. Schweppe KW. (2009). "The place of dydrogesterone in the treatment of endometriosis and adenomyosis.". Maturitas. 65 (Suppl 1): S23–7. doi:10.1016/j.maturitas.2009.11.011. PMID 19945806. - Accessed: October 12, 2016.
  9. Dennerstein L; Morse C; Gotts G; Brown J; Smith M; Oats J; Burrows G. (1986). "Treatment of premenstrual syndrome. A double-blind trial of dydrogesterone.". J Affect Disord. 11: 199–205. PMID 2951407. - Accessed: October 12, 2016.
  10. "Postmenopausal Hormone Therapy: An Endocrine Society Scientific Statement". The Journal of Clinical Endocrinology and Metabolism. - Accessed: October 12, 2016. (Accessed on 11/28/16)
  11. Source: HSDB Record Name: DYDROGESTERONE - Accessed: October 12, 2016. (Accesed on 11/30/16)
  12. Daniel R. Mishell; Thomas H. Kirschbaum; C. Paul Morrow. 1990 The Year Book of Obstetrics and Gynecology. Year Book Medical.
  13. "Dydrogesterone/Estradiol (Generic Femoston 1/10mg tablets)". National Health Service (England).
  14. - Accessed: July 14, 2016.
  15. - Accessed: July 3, 2016.
  16. Cancer.Net (2014). - Accessed: July 3, 2016.
  17. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). - Accessed: May 28, 2016.
  18. National Institute of Drug Abuse (2010). - Accessed: July 21, 2016.
  19. eMedicinehealth (2016). - Accessed: July 21, 2016.
  20. Centers for Disease Control and Prevention (2010). - Accessed: July 21, 2016.
  21. Centers for Disease Control and Prevention. December 12, 2011. - Accessed: June 10, 2016.
  22. The Center for Improving Medication Management and the National Council on Patient Information and Education. - Accessed: June 10, 2016.
  23. U.S. Food and Drug Administration. December 24, 2013. - Accessed: June 10, 2016.
  24. World Health Organization: - Accessed: July 1, 2016.
  25. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
  26. Harvard Medical School (2016). - Accessed: May 1, 2016.

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  • "Dydrogesterone - Uses, Side-effects, Reviews, and Precautions -" N.p., n.d. Web. 15 Dec. 2017.

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Last updated date

This page was last updated on 12/01/2017.
This page provides information for Dydrogesterone in English.
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