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What is Colistin Sulphate?

Colistin Sulphate is used for Treatment of infection due to gram-negative bacilli such as pseudomonas aeruginosa and other conditions. This salt may also be used for purposes not listed in this medication guide. Detailed information related to Colistin Sulphate's uses, side-effects, reviews, questions, interactions, and precautions is as follows:

Colistin Sulphate Uses

Colistin Sulphate is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
  • Treatment of infection due to gram-negative bacilli such as pseudomonas aeruginosa
  • Colistin Sulphate may also be used for purposes not listed here.
References: 1
Learn more: Uses

Colistin Sulphate Working, Mechanism of Action and Pharmacology

Colistin Sulphate improves the patient's condition by performing the following functions:
References: 1

Colistin Sulphate - Side-effects

The following is a list of possible side-effects that may occur in medicines that contain Colistin Sulphate. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
References: 1
Learn more: Side-effects

Colistin Sulphate - Precautions & How to Use

Before using Colistin Sulphate, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
  • Apnea
  • Avoid driving
  • Clostridium difficile associated diarrhea
  • Complete the full course of therapy
  • Contact doctor if developing watery and bloody stools
  • Diarrhea is a common problem
References: 1, 1

Where to Buy Colistin Sulphate

Click here to find nearby pharmacies/medical stores where you can buy Colistin Sulphate.

Colistin Sulphate - Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Colistin Sulphate may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Colistin Sulphate may interact with the following drugs and products:
References: 1
Learn more: Interactions

Colistin Sulphate - Contraindications

Hypersensitivity to Colistin Sulphate is a contraindication. In addition, Colistin Sulphate should not be used if you have the following conditions:
References: 1
Learn more: Contraindications

Colistin Sulphate - Frequently asked Questions

  • Is Colistin Sulphate safe to consume or apply when pregnant?
    References: 1
  • Is Colistin Sulphate safe while breastfeeding?
    Please discuss the risks and benefits with your doctor.
    References: 1
  • Is it safe to drive or operate heavy machinery when consuming?
    If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Colistin Sulphate medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Colistin Sulphate. Always consult with your doctor for recommendations specific to your body and health conditions.
  • Is this medicine or product addictive or habit forming?
    Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
  • Can it be stopped immediately or do I have to slowly ween off consumption?
    Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on Colistin Sulphate

Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
References: 2, 3, 4, 5

Overdosage of Colistin Sulphate

  • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Colistin Sulphate, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
  • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
  • Please consult your physician or pharmacist or product package for more information.
References: 6, 7, 8

Storage of Colistin Sulphate

  • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
  • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Colistin Sulphate.
References: 9, 10, 11, 12

Expired Colistin Sulphate

  • Taking a single dose of expired Colistin Sulphate is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
References: 13, 14

Dosage Information

Please consult your physician or pharmacist or refer to product package.

Questions - Colistin Sulphate

No questions have been asked.

News and Updates

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Colistin Sulphate - Demographic Information


  1. Prescribing information. Coly-Mycin M Parenteral. Colistimethate for Injection.Accessed 11/20/2016. - Accessed: October 12, 2016.
  2. - Accessed: July 14, 2016.
  3. - Accessed: July 3, 2016.
  4. Cancer.Net (2014). - Accessed: July 3, 2016.
  5. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). - Accessed: May 28, 2016.
  6. National Institute of Drug Abuse (2010). - Accessed: July 21, 2016.
  7. eMedicinehealth (2016). - Accessed: July 21, 2016.
  8. Centers for Disease Control and Prevention (2010). - Accessed: July 21, 2016.
  9. Centers for Disease Control and Prevention. December 12, 2011. - Accessed: June 10, 2016.
  10. The Center for Improving Medication Management and the National Council on Patient Information and Education. - Accessed: June 10, 2016.
  11. U.S. Food and Drug Administration. December 24, 2013. - Accessed: June 10, 2016.
  12. World Health Organization: - Accessed: July 1, 2016.
  13. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
  14. Harvard Medical School (2016). - Accessed: May 1, 2016.

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  • Colistin Sulphate - Uses, Side-effects, Reviews, and Precautions - (n.d.). Retrieved December 15, 2017, from

MLA Style Citation

  • "Colistin Sulphate - Uses, Side-effects, Reviews, and Precautions -" N.p., n.d. Web. 15 Dec. 2017.

Chicago Style Citation

  • "Colistin Sulphate - Uses, Side-effects, Reviews, and Precautions -" Accessed December 15, 2017.

Last updated date

This page was last updated on 12/12/2017.
This page provides information for Colistin Sulphate in English.
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