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    What is Betahistine / Domperidone?

    Betahistine / Domperidone is used for Meniere disease, Meniere's disease, Vertigo, Treatment for symptoms associated with idiopathic or diabetic gastroparesis, Treatment for intractable nausea and vomiting and other conditions. This salt combination may also be used for purposes not listed in this medication guide. Detailed information related to Betahistine / Domperidone's uses, side-effects, reviews, questions, interactions, and precautions is as follows:

    Betahistine / Domperidone Uses

    Betahistine / Domperidone is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
    References: 1, 2, 3
    Learn more: Uses

    Betahistine / Domperidone Working, Mechanism of Action and Pharmacology

    Betahistine / Domperidone improves the patient's condition by performing the following functions:
    References: 1, 3

    Betahistine / Domperidone - Side-effects

    The following is a list of possible side-effects that may occur in medicines that contain Betahistine / Domperidone. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
    If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
    References: 3, 4
    Learn more: Side-effects

    Betahistine / Domperidone - Precautions & How to Use

    Before using Betahistine / Domperidone, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
    • Asthma
    • Avoid driving or operating machinery
    • Concurrent use with QT prolongating agents
    • Discontinue use if experiencing signs or symptoms associated with cardiac arrhythmia
    • Existing rash or cold
    • Low blood pressure
    References: 3, 3, 5

    Betahistine / Domperidone - Drug Interactions

    If you use other drugs or over the counter products at the same time, the effects of Betahistine / Domperidone may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Betahistine / Domperidone may interact with the following drugs and products:
    • Amiodarone
    • Amprenavir
    • Antacids
    • Antihistamines
    • Aprepitant
    • Atazanavir
    References: 3, 5
    Learn more: Interactions

    Betahistine / Domperidone - Contraindications

    Hypersensitivity to Betahistine / Domperidone is a contraindication. In addition, Betahistine / Domperidone should not be used if you have the following conditions:
    References: 3, 5
    Learn more: Contraindications

    Where to Buy Betahistine / Domperidone

    Click here to find nearby pharmacies/medical stores where you can buy Betahistine / Domperidone.

    Betahistine / Domperidone - Frequently asked Questions

    • Is Betahistine / Domperidone safe to consume or apply when pregnant?
      • Betahistine: Please consult with your doctor for case-specific recommendations.
      • Domperidone: Please consult with your doctor for case-specific recommendations.
      References: 3 5
    • Is Betahistine / Domperidone safe while breastfeeding?
      • Betahistine: Please discuss the risks and benefits with your doctor.
      • Domperidone: No
      References: 3 5
    • Can Betahistine / Domperidone be used for meniere disease and meniere's disease?
      Yes, meniere disease and meniere's disease are among the most common reported uses for Betahistine / Domperidone. Please do not use Betahistine / Domperidone for meniere disease and meniere's disease without consulting first with your doctor. Click here and view survey results to find out what other patients report as common uses for Betahistine / Domperidone.
    • Is it safe to drive or operate heavy machinery when consuming?
      If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Betahistine / Domperidone medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Betahistine / Domperidone. Always consult with your doctor for recommendations specific to your body and health conditions.
    • Is this medicine or product addictive or habit forming?
      Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
    • Can it be stopped immediately or do I have to slowly ween off consumption?
      Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

    Other important Information on Betahistine / Domperidone

    Missing a dose

    In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
    References: 6, 7, 8, 9

    Overdosage of Betahistine / Domperidone

    • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Betahistine / Domperidone, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
    • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
    • Please consult your physician or pharmacist or product package for more information.
    References: 10, 11, 12

    Storage of Betahistine / Domperidone

    • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
    • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Betahistine / Domperidone.
    References: 13, 14, 15, 16

    Expired Betahistine / Domperidone

    • Taking a single dose of expired Betahistine / Domperidone is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
    References: 17, 18

    Dosage Information

    Please consult your physician or pharmacist or refer to product package.

    Questions - Betahistine / Domperidone

    No questions have been asked.

    News and Updates

    Latest news and updates related to Betahistine / Domperidone. Subscribe to get latest posts via email or subscribe to a RSS feed.
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    Betahistine / Domperidone - Demographic Information


    1. Lacour M, van de Heyning PH, Novotny M, Tighilet B. Betahistine in the treatment of Menier's disease. PMC Neuropsychiatr Dis Treat. 2007 Aug; 3(4): 429–440. Published online 2007 Aug. - Accessed: October 12, 2016.
    2. Sokolova L, Hoerr R, Mishchenko T. Treatment of vertigo: a randomized, double-blind trial comparing efficacy and safety of Ginkgo biloba extract EGb761 and betahistine. Int J Otolaryngol. 2014; 2014; 682439.
    3. Package insert. MOTILIUM 10 mg Tablets. Accessed 12/18/2016. - Accessed: October 12, 2016.
    4. Sokolova L, Hoerr R, Mishchenko T (2014). "Treatment of Vertigo: A Randomized, Double-Blind Trial Comparing Efficacy and Safety of Ginkgo biloba Extract EGb 761 and Betahistine". Int J Otolaryngol. 2014: 682439. doi:10.1155/2014/682439. PMC 4099171free to read. PMID 25057270. - Accessed: October 12, 2016.
    5. Accord Healthcare Limited. Betahistine dihydrochloride [package leaflet]. June 2015. . - Accessed: October 12, 2016. Accessed October 1, 2016.
    6. - Accessed: July 14, 2016.
    7. - Accessed: July 3, 2016.
    8. Cancer.Net (2014). - Accessed: July 3, 2016.
    9. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). - Accessed: May 28, 2016.
    10. National Institute of Drug Abuse (2010). - Accessed: July 21, 2016.
    11. eMedicinehealth (2016). - Accessed: July 21, 2016.
    12. Centers for Disease Control and Prevention (2010). - Accessed: July 21, 2016.
    13. Centers for Disease Control and Prevention. December 12, 2011. - Accessed: June 10, 2016.
    14. The Center for Improving Medication Management and the National Council on Patient Information and Education. - Accessed: June 10, 2016.
    15. U.S. Food and Drug Administration. December 24, 2013. - Accessed: June 10, 2016.
    16. World Health Organization: - Accessed: July 1, 2016.
    17. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
    18. Harvard Medical School (2016). - Accessed: May 1, 2016.

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    Last updated date

    This page was last updated on 11/04/2017.
    This page provides information for Betahistine / Domperidone in English.
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