Sunday, February 11, 2018 -- Existing treatments for kidney disease can be costly, invasive, ineffective, and completely inaccessible to some. One new study shows how human kidney tissue could be grown inside of a living organism, demonstrating the potential to one day save the lives of millions. The post We Can Now Use Stem Cells to Grow Functioning Kidney Tissue appeared first on Futurism.
Thursday, February 15, 2018 -- Researchers from the Stanford University School of Medicine have developed a potentially viable vaccine for cancer. It uses stem cells that can grow into various types of other cells to train the immune system to target cancer before it takes hold. The post New Stem Cell Study Could Be the Start of Personalized Cancer Vaccines appeared first on Futurism.
Thursday, February 15, 2018 -- Injections of killed stem cells, designed to help the immune system recognise cancers, have been found to protect mice from developing tumours
Saturday, February 10, 2018 -- MedicalResearch.com Interview with: Michael G. Chez, M.D. Director of Pediatric Neurology Sutter Memorial Hospital Director of the Pediatric Epilepsy and Autism Programs Sutter Neuroscience Group MedicalResearch.com: What is the background for this study? What are the main findings? Response: The study looked at … Continue reading →
Wednesday, February 14, 2018 -- Studies in fruit flies have shown how cells in the offspring of older fathers can replace copies of genes that have been lost due to aging. The findings by Yukiko Yamashita, Ph.D., a Howard Hughes Medical Institute investigator, and colleagues at the University of Michigan Life Sciences Institute provide clues as to how some cells could overcome genomic shrinkage that appears to occur as an organism ages. If the same results can be confirmed in humans, they could offer a new level of understanding about how cells deteriorate with time. These findings are reported in eLife, in a paper entitled "T ransgenerational Dynamics of rDNA Copy Number in Drosophila Male Germline Stem Cells. " Dr. Yamashita’s team looked
Tuesday, February 13, 2018 -- Researchers may have found a way to reduce ongoing heart damage that occurs long after a severe heart attack by improving the longevity of stem cells injected into the heart.
Saturday, February 10, 2018 -- A research team from Tongji University in China have made a breakthrough in human lung regeneration technology. For the first time, researchers have regenerated patients' damaged lungs using autologous lung stem cell transplantation in a pilot clinical trial.
Thursday, February 15, 2018 -- The proper function of blood vessels is essential to life: blood vessels are responsible for transporting oxygen-rich red blood cells, nutrients, and immune cells throughout the body, to name just a few functions. Defects in blood vessels can correspondingly lead to a variety of life-threatening diseases.
Tuesday, February 13, 2018 -- Fujifilm said it plans to use stem cells developed by Cellular Dynamics International, a Wisconsin-based company it owns, as part of a new partnership between Fujifilm and Takeda Pharmaceutical that’s aimed at developing regenerative medicine therapies. Takeda and Fujifilm, both headquartered in Japan, recently signed a contract giving Takeda the global commercialization rights to therapies […]
Tuesday, February 13, 2018 -- The AlgTube 3D culture system allows stem cells to grow within a physiologically relevant environment.
Thursday, February 15, 2018 -- HLA-DPB1 T-cell epitope (TCE) mismatching algorithm and rs9277534 SNP at the 3' untranslated region (3'UTR) in the HLA-DPB1 gene are key factors for transplant-related events in unrelated hematopoietic cell transplantation (UR-HCT). However, the association of these 2 mechanisms has not been elucidated. We analyzed 19 frequent HLA-DPB1 alleles derived from Japanese healthy subjects by next-generation sequencing of the entire HLA-DPB1 gene region and multi-SNP data of the HLA region in 1589 UR-HCT pairs. The risk of acute graft-versus-host disease (aGVHD) was analyzed in 1286 patients with single HLA-DPB1 mismatch UR-HCT. The phylogenetic tree constructed using the entire gene region demonstrated that HLA-DPB1 alleles were divided into 2 groups, HLA-DP2 and HLA-DP5. Although a phylogenetic relationship in the genomic region
Wednesday, February 14, 2018 -- Past investigations on stem cell-mediated recovery after stroke have limited their focus on the extent and morphological development of the ischemic lesion itself over time or on the integration capacity of the stem cell graft ex vivo. However, an assessment of the long-term functional and structural improvement in vivo is essential to reliably quantify the regenerative capacity of cell implantation after stroke. We induced ischemic stroke in nude mice and implanted human neural stem cells (H9 derived) into the ipsilateral cortex in the acute phase. Functional and structural connectivity changes of the sensorimotor network were noninvasively monitored using magnetic resonance imaging for 3 months after stem cell implantation. A sharp decrease of the functional sensorimotor network extended even to
Wednesday, February 14, 2018 -- The embryonic formation of midbrain dopaminergic (mDA) neurons in vivo provides critical guidelines for the in vitro differentiation of mDA neurons from stem cells, which are currently being developed for Parkinson's disease cell replacement therapy. Bone morphogenetic protein (BMP)/SMAD inhibition is routinely used during early steps of stem cell differentiation protocols, including for the generation of mDA neurons. However, the function of the BMP/SMAD pathway for in vivo specification of mammalian mDA neurons is virtually unknown. Here, we report that BMP5/7-deficient mice (Bmp5–/–; Bmp7–/–) lack mDA neurons due to reduced neurogenesis in the mDA progenitor domain. As molecular mechanisms accounting for these alterations in Bmp5–/–; Bmp7–/– mutants, we have identified expression changes of the BMP/SMAD target genes MSX1/2 (msh
Thursday, February 15, 2018 -- Induced pluripotent stem cells have the power to transform into any cell in the body, making them a prime candidate for regenerative medicine. Scientists at Stanford University believe stem cells can also teach the immune system to recognize and attack cancer—and they tested the concept in mouse models of breast cancer.
Wednesday, February 14, 2018 -- Popularizing stem cell therapies will require the systematic, consistent production of billions of cells and carefully monitoring their production to prevent unintended side effects. Even now, growing and differentiating groups of cells for lab experiments is a process requiring close quality control. The National Institute of Standards and Technology (NIST) recognized the need for a […]
Thursday, February 15, 2018 -- Stem cells and cancer cells have enough molecular similarities that the former can be used to trigger immunity against the latter.