Thursday, January 04, 2018 -- Phase 2b data for an oral leuprolide formulation gives Enteris boost to aim for the next stage.
Thursday, December 28, 2017 -- Endometriosis diagnosis can be difficult, even though the disease is common. Researchers investigate the links between symptoms and a diagnosis. Endometriosis is a condition that affects millions of women and causes chronic pain and infertility. In women who have endometriosis, the tissues that line the uterus grow outside the uterus in other parts of the […] The post Endometriosis Diagnosis: Is There a Symptom Pattern? appeared first on Medical News Bulletin | Health News and Medical Research.
Thursday, December 28, 2017 -- SALT LAKE CITY, Dec. 28, 2017 -- Predictive Technology Group, Inc. (OTC PINK:PRED), a life sciences technology holding company, announced today the issuance of U.S. patent 9,840,738 directed to treating patients...
Monday, November 20, 2017 -- Endometriosis causes symptoms of mental health problems in mice, and the one in ten women who have the condition are more likely to have depression or anxiety
Tuesday, November 07, 2017 -- Researchers from Nanjing Traditional Chinese Medicine University and Haian Traditional Chinese Medicine Hospital find acupuncture combined with herbs effective for the alleviation of endometriosis. Two patient groups were compared in a six month clinical trial. One group received Traditional Chinese Medicine (acupuncture and herbs) and the other group received mifepristone (RU-486®, a synthetic steroid that inhibits progesterone action, used for the treatment endometriosis or as an abortifacient). Ultrasonography for detection of endometriomas and growths in addition to blood tests (cancer antigen 125, anti-endometrial antibody) were used to determine treatment efficacy. The bloodwork was equivalent and ultrasonography finds both TCM and mifepristone drug therapy equal in effectiveness for the reduction of endometriomas or other growths.
Wednesday, November 01, 2017 -- Researchers examined the efficacy of FlexibleMIB (ethinylestradiol/drospirenone) vs placebo as therapy for endometriosis-related pain.
Wednesday, November 01, 2017 -- Purpose: Endometrial cancer (EC) diagnosis relies on the observation of tumor cells in endometrial biopsies obtained by aspiration (i.e., uterine aspirates), but it is associated with 22% undiagnosed patients and up to 50% of incorrectly assigned EC histotype and grade. We aimed to identify biomarker signatures in the fluid fraction of these biopsies to overcome these limitations. Experimental Design: The levels of 52 proteins were measured in the fluid fraction of uterine aspirates from 116 patients by LC-PRM, the latest generation of targeted mass-spectrometry acquisition. A logistic regression model was used to assess the power of protein panels to differentiate between EC and non-EC patients and between EC histologic subtypes. The robustness of the panels was assessed by the
Friday, October 27, 2017 -- Looming generic competition for AbbVie’s top-selling drug, Humira, threatens the top line while putting extreme pressure on the company to deliver follow-up blockbusters from its pipeline. Today the company took a big step toward putting investors’ minds at ease on both counts, with better-than-expected third-quarter results.
Wednesday, October 04, 2017 -- A flexible extended regimen of 20 mg ethinylestradiol and 3 mg drospirenone (FlexibleMIB) was shown to be superior to placebo for reducing endometriosis-related pain.
Thursday, September 21, 2017 -- A new medication under study modulates the body’s production of estrogen (rather than shutting it off) may provide a better option for women seeking treatment for endometriosis. The post New treatment for endometriosis on the horizon appeared first on Harvard Health Blog.
Wednesday, September 13, 2017 -- A new meta-analysis shows that pregnant women with endometriosis are at greater risk for a host of complications during pregnancy and at delivery, including preterm birth and cesarean section. The study was published in the journal Fertility and Sterility.
Tuesday, September 12, 2017 -- by Shaojie Ding, Libo Zhu, Yonghong Tian, Tianhong Zhu, Xiufeng Huang, Xinmei Zhang The purinergic receptor P2X ligand-gated ion channel 3 (P2X3) is crucially involved in peripheral nociceptive processes of somatic and visceral pain. Endometriosis pain is considered as a kind of inflammatory and neuropathic pain. However, whether P2X3 is involved in endometriosis pain has not been reported up to date. Here, we aimed to determine whether P2X3 expression in endometriotic lesions is involved in endometriosis pain, which is regulated by inflammatory mediators through extracellular regulated protein kinases (ERK) signalling pathway. We found that P2X3 expressions in endometriosis endometrium and endometriotic lesions were both significantly higher as compared with control endometrium (P<0.05), and both positively correlated with pain (P<0.05).
Tuesday, September 12, 2017 -- (Reuters Health) - Women who nurse their babies are less likely to develop endometriosis, and the longer they breastfeed, the lower their risk, a new study shows.
Saturday, September 09, 2017 -- A longer duration of breastfeeding is associated with a lower risk for endometriosis in the mother, according to a study in The BMJ.
Friday, September 08, 2017 -- Duration of total and exclusive breastfeeding was significantly associated with a decreased risk of endometriosis.
Wednesday, September 06, 2017 -- Elagolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, was evaluated in two Phase 3 clinical studies in about 1,700 women with moderate-to-severe endometriosis-associated pain.
Friday, September 01, 2017 -- A new study finds that women who breast-feed have a lower risk of being diagnosed with endometriosis, with longer duration conferring the lowest risk.
Thursday, August 31, 2017 -- Endometriosis is a chronic and incurable gynecologic disorder that affects approximately 10 percent of women in the United States. Its symptoms can be debilitating and include chronic pelvic pain, painful periods and pain during intercourse.
Tuesday, July 11, 2017 -- Researchers find acupuncture more effective than hormone drug therapy for the treatment of endometriosis. Acupuncture relieves menstrual pain due to endometriosis, reduces the size of pelvic masses, lowers CA125 levels, and reduces the recurrence rate of endometriosis. CA125 a is biomarker for several types of cancer and benign conditions including endometriosis and menstrual disorders. Researchers at Tongji University hospital compared acupuncture with standard drug therapy. Patients receiving acupuncture achieved a 92.0% total effective rate. Patients receiving mifepristone achieved a 52.0% total effective rate. Mifepristone, also known by its trademarked name RU-486, is a synthetic steroid that inhibits progesterone action and is used for the treatment endometriosis and also for inducing abortions. Notably, low doses of “mifepristone inhibits
Monday, June 26, 2017 -- Gonadotropin-releasing hormone antagonist elagolix demonstrated clinical improvement for women with endometriosis-related pain.