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    Thursday, January 11, 2018 -- Virus hides in plain sight by being less aggressive

    Thursday, December 28, 2017 -- Antibodies from mice vaccinated with one strain of dengue virus while pregnant have been found to worsen symptoms in their pups infected with other strains.

    Thursday, December 28, 2017 -- Scientists in Australia and China have identified an antibody protects against all four types of dengue viruses.

    Wednesday, December 13, 2017 -- CHICAGO/LONDON (Reuters) - When French drugmaker Sanofi published the results of clinical trials of children given its dengue vaccine two years ago, the overall findings were that it protected against the world's biggest and fastest growing mosquito-borne disease.

    Monday, December 11, 2017 -- The Dengue virus has been difficult to control in the Philippines, and the country has been attempting to immunize its children with the new dengue vaccine Dengvaxia since January 2016.

    Friday, December 08, 2017 -- A species of fungus that lives in the gut of some Aedes aegypti mosquitoes increases the ability of dengue virus to survive in the insects, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

    Wednesday, December 06, 2017 -- A team of researchers in China report that at periods of prolonged high temperatures favor the growth and spread of the dengue virus.

    Monday, December 04, 2017 -- (Reuters) - The World Health Organization said on Monday it hopes to review safety data on Sanofi's dengue vaccine this month, while the Philippines ordered an investigation of its now suspended massive immunization program after the French drugmaker said it could actually worsen the disease in some cases.

    Monday, December 04, 2017 -- BRASILIA (Reuters) - The Brazilian government said on Monday it has suggested restrictions on the use of a dengue vaccine that has been suspended elsewhere after French drug company Sanofi SA said it could worsen the disease in some cases.

    Friday, December 01, 2017 -- Stephanie Soucheray | News Reporter | CIDRAP NewsDec 01, 2017A leading dengue vaccine researcher says the move is not surprising, while Sanofi says antibody-dependent enhancement cannot be the whole story surrounding vaccine performance.

    Friday, December 01, 2017 -- Receiving a dengue vaccine at an elementary school near Manila in April.

    Thursday, November 30, 2017 -- Drugmaker Sanofi says that its dengue vaccine, the world's first, should only be given to people who have previously been sickened by the virus, according to new long-term data.

    Wednesday, November 29, 2017 -- Interview with: Vianney Tricou DPhil Takeda Vaccines Pte Ltd Singapore What is the background for this study? What are the main findings? Response: Dengue fever is a painful, debilitating mosquito-borne disease caused by any one of the four closely … Continue reading →

    Monday, November 27, 2017 -- In 2015, Malaysia reported more than 120,000 dengue fever cases and some 320 deaths. Last year, the numbers dropped to just a hair above 100,000 and about 230 deaths. In both years, dengue was the number one rated infectious disease in the country. As 2017 comes to a close, the numbers are yet lower than […] The post Dengue still #1 infectious disease in Malaysia despite recent drop in cases appeared first on Outbreak News Today.

    Saturday, November 25, 2017 -- (MENAFN - NewsBytes) India may have a vaccine for dengue by 2019-end 25 Nov 2017 We might have a vaccine for dengue by the end of 2019. To test its viability, the Drug Con...

    Tuesday, November 21, 2017 -- Global health officials say the dengue fever outbreak in the African nation of Burkina Faso continues to spread particularly in the central region of the country, which contains the capital city of Ouagadougou. Since our last report, the number of cases have essentially doubled in the country (6,699 suspected, probable or confirmed cases and 13 deaths […] The post Africa: Dengue ‘declining slightly’ in Burkina Faso appeared first on Outbreak News Today.

    Thursday, November 16, 2017 -- For dengue viruses 1 to 4 (DENV1-4), a specific range of antibody titer has been shown to enhance viral replication in vitro and severe disease in animal models. Although suspected, such antibody-dependent enhancement of severe disease has not been shown to occur in humans. Using multiple statistical approaches to study a long-term pediatric cohort in Nicaragua, we show that risk of severe dengue disease is highest within a narrow range of preexisting anti-DENV antibody titers. By contrast, we observe protection from all symptomatic dengue disease at high antibody titers. Thus, immune correlates of severe dengue must be evaluated separately from correlates of protection against symptomatic disease. These results have implications for studies of dengue pathogenesis and for vaccine development,

    Monday, November 13, 2017 -- While the peak of the dengue fever outbreak in Fiji is long past, the number of cases recorded this year are triple what they were in 2016 during the same period. According to a Fiji Village report, Acting National Advisor for Communicable Diseases, Doctor Aalisha Sahu-Khan said 2,699 dengue cases have been reported year-to-date, while 889 were […] The post Dengue cases triple in Fiji in 2017 appeared first on Outbreak News Today.

    Monday, November 13, 2017 -- Manifestations of Zika virus (ZIKV) infection differ drastically. Sometimes they are catastrophic, most notably when they cause microcephaly in some babies born to infected mothers. At other times, they are mild and fleeting, suggesting that unknown factors temper Zika infections’ severity. Recently, dengue virus emerged as a prime suspect because it shares many genetic and […] The post Prior dengue exposure shows ‘cross-protection’ against Zika: Study appeared first on Outbreak News Today.

    Saturday, November 11, 2017 -- The Philippines has reported a more than 40 percent decrease in dengue cases nationwide in 2017 to date compared to the same period in 2016. During the first nine months of the year, health officials have reported a total of 97,287 dengue cases including 526 deaths. This number is 41.8% lower (167,102) than that for the […] The post Cebu dengue cases just a half of 2016 numbers appeared first on Outbreak News Today.

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