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Avastatin Tablet

Uses, Side-effects, Reviews, and Precautions

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What is Avastatin?

Avastatin Tablet is used for High cholesterol, Cardiovascular disease, Heart complications, Dyslipidemia, Prevention of atherosclerotic stroke, Prevention of heart attack and other conditions. Avastatin Tablet may also be used for purposes not listed in this medication guide.
Avastatin Tablet contains Atorvastatin as an active ingredient.
Avastatin Tablet works by inhibiting HMG-CoA reductase and reduces triglycerides levels in the blood.
Edruc manufactures Avastatin Tablet.
Detailed information related to Avastatin Tablet's uses, composition, dosage, side effects and reviews is listed below.

Avastatin Tablet Uses

Avastatin Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
References: 1, 2, 3, 4, 5, 6
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Learn more: Uses

Avastatin Tablet Working, Mechanism of Action and Pharmacology

Avastatin Tablet improves the patient's condition by performing the following functions:
References: 1, 7

Avastatin Tablet - Composition and Active Ingredients

Avastatin Tablet is composed of the following active ingredients (salts)
Please note that this medicine may be available in various strengths for each active ingredient listed above.

Avastatin Tablet - Side-effects

The following is a list of possible side-effects that may occur from all constituting ingredients of Avastatin Tablet. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
References: 8, 9, 10, 11
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Learn more: Side-effects

Avastatin Tablet - Precautions & How to Use

Before using Avastatin Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
  • Alcoholism
  • Avoid excess alcohol while on atorvastatin
  • Avoid grapefruit and grapefruit juice
  • Avoid intake of excess fat
  • Consult your doctor if you develop muscle pains, yellowing of skin/eyes, or an allergic reaction
  • Do not take atorvastatin if pregnant
References: 12, 12

Avastatin Tablet - Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Avastatin Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Avastatin Tablet may interact with the following drugs and products:
  • Antacids
  • Aprepitant
  • Azole antifungals
  • Colchicine
  • Cyclosporine
  • Diltiazem
References: 14, 15, 16, 17, 18, 19
Learn more: Interactions

Avastatin Tablet - Contraindications

Hypersensitivity to Avastatin Tablet is a contraindication. In addition, Avastatin Tablet should not be used if you have the following conditions:
References: 12
Learn more: Contraindications

Where to Buy Avastatin Tablet

Click here to find nearby pharmacies/medical stores where you can buy Avastatin Tablet.

Avastatin Tablet - Frequently asked Questions

  • Is Avastatin Tablet safe to consume or apply when pregnant?
    No
    References: 12
  • Is Avastatin Tablet safe while breastfeeding?
    No
    References: 12
  • Can Avastatin Tablet be used for high cholesterol and cardiovascular disease?
    Yes, high cholesterol and cardiovascular disease are among the most common reported uses for Avastatin Tablet. Please do not use Avastatin Tablet for high cholesterol and cardiovascular disease without consulting first with your doctor. Click here and view survey results to find out what other patients report as common uses for Avastatin Tablet.
  • Is it safe to drive or operate heavy machinery when consuming?
    If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Avastatin Tablet medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Avastatin Tablet. Always consult with your doctor for recommendations specific to your body and health conditions.
  • Is this medicine or product addictive or habit forming?
    Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
  • Can it be stopped immediately or do I have to slowly ween off consumption?
    Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on Avastatin Tablet

Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
References: 20, 21, 22, 23

Overdosage of Avastatin Tablet

  • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Avastatin Tablet, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
  • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
  • Please consult your physician or pharmacist or product package for more information.
References: 24, 25, 26

Storage of Avastatin Tablet

  • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
  • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Avastatin Tablet.
References: 27, 28, 29, 30

Expired Avastatin Tablet

  • Taking a single dose of expired Avastatin Tablet is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
References: 31, 32

Dosage Information

Please consult your physician or pharmacist or refer to product package.

Questions - Avastatin Tablet

No questions have been asked.

News and Updates

Latest news and updates related to Avastatin Tablet. Subscribe to get latest posts via email or subscribe to a RSS feed.
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Avastatin Tablet - Packages and Strengths

Please consult your physician or pharmacist or product package for this information.

Avastatin Tablet - Manufacturers

The medicine is manufactured by the following companies

Avastatin Tablet - Demographic Information

References

  1. McCrindle BW, Ose L, Marais AD (July 2003). "Efficacy and safety of atorvastatin in children and adolescents with familial hypercholesterolemia or severe hyperlipidemia: a multicenter, randomized, placebo-controlled trial". J. Pediatr. 143 (1): 74–80. doi:10.1016/S0022-3476(03)00186-0. PMID 12915827. - Accessed: October 12, 2016.
  2. Sever PS, Dahlöf B, Poulter NR, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O'Brien E, Ostergren J (April 2003). "Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial". Lancet. 361 (9364): 1149–58. doi:10.1016/S0140-6736(03)12948-0. PMID 12686036. - Accessed: October 12, 2016.
  3. Law MR, Wald NJ, Rudnicka AR (June 2003). "Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis". BMJ. 326 (7404): 1423. doi:10.1136/bmj.326.7404.1423. PMC 162260free to read. PMID 12829554. - Accessed: October 12, 2016.
  4. Wilson PW, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB (May 1998). "Prediction of coronary heart disease using risk factor categories" (PDF). Circulation. 97 (18): 1837–47. doi:10.1161/01.CIR.97.18.1837. PMID 9603539 - Accessed: October 12, 2016.
  5. Rosa GM, Carbone F, Parodi A, Massimelli EA, Brunelli C, Mach F, Vuilleumier N, Montecucco F (2014). "Update on the efficacy of statin treatment in acute coronary syndromes". Eur. J. Clin. Invest. 44 (5): 501–15. doi:10.1111/eci.12255. PMID 24601937. - Accessed: October 12, 2016.
  6. Furie KL (2012). "High-dose statins should only be used in atherosclerotic strokes". Stroke. 2012 Jul;43 (7): 1994–5. doi:10.1161/STROKEAHA.111.633339. PMID 22581818. - Accessed: October 12, 2016.
  7. Bakker-Arkema RG, Davidson MH, Goldstein RJ, Davignon J, Isaacsohn JL, Weiss SR, Keilson LM, Brown WV, Miller VT, Shurzinske LJ, Black DM (January 1996). "Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia". Journal of the American Medical Association. 275 (2): 128–33. doi:10.1001/jama.1042029. PMID 8531308. - Accessed: October 12, 2016.
  8. Lipitor: Prescribing Information. Pfizer. June 2009. - Accessed: October 12, 2016.
  9. "FDA Expands Advice on Statin Risks", FDA, 31 January 2014, retrieved 26 August 2016
  10. - Accessed: October 12, 2016.
  11. Ghirlanda G, Oradei A, Manto A, Lippa S, Uccioli L, Caputo S, Greco AV, Littarru GP (March 1993). "Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study". J Clin Pharmacol. 33 (3): 226–9. doi:10.1002/j.1552-4604.1993.tb03948.x. PMID 8463436. - Accessed: October 12, 2016.
  12. Lipitor (atorvastatin calcium) tablets prescribing information. New York, NY: Pfizer Inc. October 2012. Accessed 12 September 2016. - Accessed: October 12, 2016.
  13. Lipitor (atorvastatin calcium) tablets prescribing information. New York, NY: Pfizer Inc. October 2012. Accessed 12 September 2016. - Accessed: October 12, 2016.
  14. Williams D, Feely J (2002). "Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors". Clin Pharmacokinet. 41 (5): 343–70. doi:10.2-203. PMID 12036392. - Accessed: October 12, 2016.
  15. Mazzu AL, Lasseter KC, Shamblen EC, Agarwal V, Lettieri J, Sundaresen P (October 2000). "Itraconazole alters the pharmacokinetics of atorvastatin to a greater extent than either cerivastatin or pravastatin". Clin. Pharmacol. Ther. 68 (4): 391–400. doi:10.1067/mcp.2000.110537. PMID 11061579. - Accessed: October 12, 2016.
  16. Neuvonen PJ, Niemi M, Backman JT (December 2006). "Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance". Clin. Pharmacol. Ther. 80 (6): 565–81. doi:10.1016/j.clpt.2006.09.003. PMID 17178259. - Accessed: October 12, 2016.
  17. Backman JT, Luurila H, Neuvonen M, Neuvonen PJ (August 2005). "Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites". Clin. Pharmacol. Ther. 78 (2): 154–67. doi:10.1016/j.clpt.2005.04.007. PMID 16084850. - Accessed: October 12, 2016.
  18. McKenney JM (2005). "Efficacy and safety of rosuvastatin in treatment of dyslipidemia". Am J Health Syst Pharm. 62 (10): 1033–47. PMID 15901588. - Accessed: October 12, 2016.
  19. "Interaction between a commercially available St. John's wort product (Movina) and atorvastatin in patients with hypercholesterolemia". Eur J Clin Pharmacol. 63(10):913-6. Epub 2007 Aug 15. DOI: 10.1007/s00-x. PMID: 17701167. - Accessed: October 12, 2016.
  20. - Accessed: July 14, 2016.
  21. - Accessed: July 3, 2016.
  22. Cancer.Net (2014). - Accessed: July 3, 2016.
  23. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). - Accessed: May 28, 2016.
  24. National Institute of Drug Abuse (2010). - Accessed: July 21, 2016.
  25. eMedicinehealth (2016). - Accessed: July 21, 2016.
  26. Centers for Disease Control and Prevention (2010). - Accessed: July 21, 2016.
  27. Centers for Disease Control and Prevention. December 12, 2011. - Accessed: June 10, 2016.
  28. The Center for Improving Medication Management and the National Council on Patient Information and Education. - Accessed: June 10, 2016.
  29. U.S. Food and Drug Administration. December 24, 2013. - Accessed: June 10, 2016.
  30. World Health Organization: - Accessed: July 1, 2016.
  31. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
  32. Harvard Medical School (2016). - Accessed: May 1, 2016.

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This page was last updated on 1/18/2018.
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