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What is 12 Rene?

12 Rene Capsule is used for Diabetic polyneuropathy, Pain in neurological disorders, Treatment of megaloblastic anemias due to a deficiency of folic acid, Treatment of anemias of nutritional origin, Pregnancy, Infancy, Or childhood, Heart disease, High cholesterol and other conditions. 12 Rene Capsule may also be used for purposes not listed in this medication guide.
12 Rene Capsule contains Alpha Lipoic Acid, Folic Acid, Methylcobalamin and Pyridoxine as active ingredients.
12 Rene Capsule works by acting on megaloblastic bone marrow to produce a normoblastic marrow; modifying the electrical activity thus relaxing and slowing overactive heart muscles; works in recovery process of damaged nerve cells; inducing the oxidative stress response and chelating iron;
Skoda Health manufactures 12 Rene Capsule.
Detailed information related to 12 Rene Capsule's uses, composition, dosage, side effects and reviews is listed below.

12 Rene Capsule Uses

12 Rene Capsule is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
References: 1, 2, 3, 4, 5, 6, 7
Learn more: Uses

12 Rene Capsule Working, Mechanism of Action and Pharmacology

12 Rene Capsule improves the patient's condition by performing the following functions:
References: 1, 4, 8, 9, 10

12 Rene Capsule - Composition and Active Ingredients

12 Rene Capsule is composed of the following active ingredients (salts)
Please note that this medicine may be available in various strengths for each active ingredient listed above.

12 Rene Capsule - Side-effects

The following is a list of possible side-effects that may occur from all constituting ingredients of 12 Rene Capsule. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
References: 1, 2, 11, 12
Learn more: Side-effects

12 Rene Capsule - Precautions & How to Use

Before using 12 Rene Capsule, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
References: 1, 1, 2, 2

12 Rene Capsule - Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of 12 Rene Capsule may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. 12 Rene Capsule may interact with the following drugs and products:
  • Alcohol
  • Aminosalicylic acid
  • Antibiotics
  • Armour Thyroid
  • Barbiturates
  • Chloramphenicol
References: 1, 2
Learn more: Interactions

12 Rene Capsule - Contraindications

Hypersensitivity to 12 Rene Capsule is a contraindication. In addition, 12 Rene Capsule should not be used if you have the following conditions:
  • Double dose
  • Hypersensitivity
  • Intolerance to the drug
  • Kidney or Liver problems
  • Low blood sugar
  • Thyroid disorder
References: 1, 2
Learn more: Contraindications

Where to Buy 12 Rene Capsule

Click here to find nearby pharmacies/medical stores where you can buy 12 Rene Capsule.

12 Rene Capsule - Frequently asked Questions

  • Is 12 Rene Capsule safe to consume or apply when pregnant?
    • Folic Acid: Yes
    • Pyridoxine: Please consult with your doctor for case-specific recommendations.
    • Methylcobalamin: Please consult with your doctor for case-specific recommendations.
    • Alpha Lipoic Acid: Please consult with your doctor for case-specific recommendations.
    References: 1 2
  • Is 12 Rene Capsule safe while breastfeeding?
    • Folic Acid: Yes
    • Pyridoxine: Please discuss the risks and benefits with your doctor.
    • Methylcobalamin: No
    • Alpha Lipoic Acid: Please discuss the risks and benefits with your doctor.
    References: 1 2
  • Can 12 Rene Capsule be used for diabetic polyneuropathy and pain in neurological disorders?
    Yes, diabetic polyneuropathy and pain in neurological disorders are among the most common reported uses for 12 Rene Capsule. Please do not use 12 Rene Capsule for diabetic polyneuropathy and pain in neurological disorders without consulting first with your doctor. Click here and view survey results to find out what other patients report as common uses for 12 Rene Capsule.
  • Is it safe to drive or operate heavy machinery when consuming?
    If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using 12 Rene Capsule medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using 12 Rene Capsule. Always consult with your doctor for recommendations specific to your body and health conditions.
  • Is this medicine or product addictive or habit forming?
    Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
  • Can it be stopped immediately or do I have to slowly ween off consumption?
    Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on 12 Rene Capsule

Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
References: 13, 14, 15, 16

Overdosage of 12 Rene Capsule

  • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of 12 Rene Capsule, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
  • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
  • Please consult your physician or pharmacist or product package for more information.
References: 17, 18, 19

Storage of 12 Rene Capsule

  • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
  • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard 12 Rene Capsule.
References: 20, 21, 22, 23

Expired 12 Rene Capsule

  • Taking a single dose of expired 12 Rene Capsule is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
References: 24, 25

Dosage Information

Please consult your physician or pharmacist or refer to product package.

Questions - 12 Rene Capsule

No questions have been asked.

News and Updates

Latest news and updates related to 12 Rene Capsule. Subscribe to get latest posts via email or subscribe to a RSS feed.
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12 Rene Capsule - Packages and Strengths

12 Rene Capsule is available in the following packages and strengths
12 Rene Capsule - Packages: 10 Capsule

12 Rene Capsule - Manufacturers

The medicine is manufactured by the following companies

12 Rene Capsule - Demographic Information


  1. DailyMed LABEL: FOLIC ACID- folic acid tablet. Accessed on 2/3/17. - Accessed: October 12, 2016.
  2. DailyMed LABEL: PYRIDOXINE HYDROCHLORIDE - pyridoxine hydrochloride injection, solution - Accessed: October 12, 2016. (Accessed on 2/6/17)
  3. Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics - Accessed: October 12, 2016.
  4. Shay, KP; Moreau, RF; Smith, EJ; Hagen, TM (June 2008). "Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity". IUBMB Life. 60 (6): 362–7. doi:10.1002/iub.40. PMID 18409172. - Accessed: October 12, 2016.
  5. Ziegle, D.; Reljanovic, M; Mehnert, H; Gries, F. A. (1999). "α-Lipoic acid in the treatment of diabetic polyneuropathy in Germany". Experimental and Clinical Endocrinology & Diabetes. J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart. 107 (7): 421–30. doi:10.1055/s-0029-1212132. PMID 10595592. Retrieved 24 August 2016. - Accessed: October 12, 2016.
  6. Retrieved on 10/18/2016. Kisely S, Forbes M, Sawyer E, Black E, Lalloo R. A systematic review of randomized trials for the treatment of burning mouth syndrome. J Psychosom Res. 2016 Jul;86:39-46. doi: 10.1016/j.jpsychores.2016.05.001. Epub 2016 May 9. - Accessed: October 12, 2016.
  7. Sarezky D, Retrieved on 10/18/2016. Raquib AR, Dunaief JL, Kim BJ. Clin Ophthalmol. 2016 Sep 29;10:1899-1903. eCollection 2016. Tolerability in the elderly population of high-dose alpha lipoic acid: a potential antioxidant therapy for the eye. - Accessed: October 12, 2016.
  8. Pubchem Pyridoxine - Accessed: October 12, 2016. (Accessed on 2/6/17)
  9. Evaluations of Drug Interactions. 2nd ed. and supplements. Washington, DC: American Pharmaceutical Assn., 1976, 1978., p. 450 Source: HSDB Record Name: CYANOCOBALAMIN - Accessed: October 12, 2016.
  10. Retrieved on 10/18/2016. Sarezky D, Raquib AR, Dunaief JL, Kim BJ. Clin Ophthalmol. 2016 Sep 29;10:1899-1903. eCollection 2016. Tolerability in the elderly population of high-dose alpha lipoic acid: a potential antioxidant therapy for the eye. - Accessed: October 12, 2016.
  11. Autism Research and Treatment Volume 2013 (2013), Article ID 609705, 9 pages - Accessed: October 12, 2016. Clinical Study Effectiveness of Methylcobalamin and Folinic Acid Treatment on Adaptive Behavior in Children with Autistic Disorder Is Related to Glutathione Redox Status - Accessed: October 12, 2016.
  12. Retrieved on 10/18/2016. Tang J, Wingerchuk DM, Crum BA, Rubin DI, Demaerschalk BM. Alpha-lipoic acid may improve symptomatic diabetic polyneuropathy. Neurologist. 2007 May;13(3):164-7. - Accessed: October 12, 2016.
  13. - Accessed: July 14, 2016.
  14. - Accessed: July 3, 2016.
  15. Cancer.Net (2014). - Accessed: July 3, 2016.
  16. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). - Accessed: May 28, 2016.
  17. National Institute of Drug Abuse (2010). - Accessed: July 21, 2016.
  18. eMedicinehealth (2016). - Accessed: July 21, 2016.
  19. Centers for Disease Control and Prevention (2010). - Accessed: July 21, 2016.
  20. Centers for Disease Control and Prevention. December 12, 2011. - Accessed: June 10, 2016.
  21. The Center for Improving Medication Management and the National Council on Patient Information and Education. - Accessed: June 10, 2016.
  22. U.S. Food and Drug Administration. December 24, 2013. - Accessed: June 10, 2016.
  23. World Health Organization: - Accessed: July 1, 2016.
  24. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
  25. Harvard Medical School (2016). - Accessed: May 1, 2016.

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APA Style Citation

  • 12 Rene Capsule - Uses, Side-effects, Reviews, and Precautions - Skoda Health - - India. (n.d.). Retrieved January 19, 2018, from

MLA Style Citation

  • "12 Rene Capsule - Uses, Side-effects, Reviews, and Precautions - Skoda Health - - India" N.p., n.d. Web. 19 Jan. 2018.

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  • "12 Rene Capsule - Uses, Side-effects, Reviews, and Precautions - Skoda Health - - India" Accessed January 19, 2018.

Last updated date

This page was last updated on 11/21/2017.
This page provides information for 12 Rene Capsule in English.
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